DETAILS, FICTION AND LDN-27219 DRUG DEVELOPMENT PIPELINE

EC dysfunction, characterised by blunted relaxations in reaction to acetylcholine and decreased NO bioavailability, was present in the aortas of male HAS-two mice, even though it had been unaltered within the aortas of feminine HAS-two mice. Superoxide ranges enhanced and extracellular superoxide dismutase (ecSOD) expression reduced during the aort